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Rotavirus

Plain-language information about rotavirus in Canada, and the research enrolling for it now.
Plain-language guide, not medical advice
Reading time3 min
In Canada5,691 admissions, 12 hospitals, 15 years
Studies recruitingNone right now

Rotavirus causes gastroenteritis, a gut infection, mainly in babies and young children. It brings watery diarrhoea and vomiting for several days. The risk is not the diarrhoea itself but the fluid a small child loses through it.

By the numbers in Canada
5,691rotavirus hospital admissions were recorded across 12 Canadian paediatric hospitals over 15 years, from 2005 to 2020. Of those, 4,323 (76%) were acquired in the community and 1,368 (24%) were acquired in hospital.
Source: CMAJ Open, Canadian Immunization Monitoring Program Active (IMPACT) network, 2023
  • Before publicly funded immunisation, the Canadian Immunization Guide reports that of children infected with rotavirus, 36% saw a physician, 15% attended an emergency department and 7% were admitted to hospital, with hospitalisation affecting between 1 in 62 and 1 in 312 children under 5. Deaths from rotavirus were extremely rare in Canada. Source: Canadian Immunization Guide, rotavirus vaccine chapter, 2025
  • Eight provinces and two territories introduced publicly funded rotavirus immunisation between December 2010 and December 2015. PHAC's Canada Communicable Disease Report found laboratory-confirmed cases reported to the National Enteric Surveillance Program fell 54% between 2010 and 2017, with peak weekly cases dropping from 137 in 2011 to 15 in 2017. Source: Public Health Agency of Canada, Canada Communicable Disease Report 47(2), 2021
  • In the 12-hospital Canadian study, the community-acquired rotavirus rate recorded before publicly funded programmes was 60.3 per 10,000 admissions, and 11.0 per 10,000 admissions afterwards. Hospital-acquired rotavirus fell from 0.35 to 0.05 per 1,000 patient-days over the same comparison. Source: CMAJ Open, IMPACT network, 2023
WorldwideAbout one quarter of childhood diarrhoeal deaths in low- and middle-income countries were caused by rotavirus in 2021 (24.4%), an international figure that does not describe Canada, where rotavirus deaths are extremely rare.Source: Johns Hopkins Bloomberg School of Public Health, analysis published in The Lancet Global Health, 2024

What rotavirus is, and what it is not

Rotavirus spreads through stool, usually hand to mouth or from contaminated surfaces and toys. It is not food poisoning, and despite the phrase stomach flu it has nothing to do with influenza. It spreads easily enough that hand washing alone often does not stop it.

It is also not evenly hard on all ages. The Public Health Agency of Canada reports that children aged 4 to 24 months have the most severe illness, while babies under 4 months are often milder thanks to antibodies from the birth parent.

Signs and symptoms

  • Watery diarrhoea, which PHAC says usually lasts 3 to 8 days
  • Vomiting, often starting before the diarrhoea
  • Fever and stomach pain
  • Being unusually irritable, tired or hard to settle, and refusing feeds
  • Signs of dehydration: little or no urination, crying without tears, dry mouth, dizziness or unusual sleepiness

Symptoms start 1 to 3 days after exposure, and severity varies even between siblings.

An adult and a child preparing a meal together at a kitchen table.
Rotavirus immunisation in Canada is given by mouth to infants, on schedules set by each province and territory. Illustrative photograph.

What raises the risk

Some risk factors cannot be changed:

  • Being aged 4 to 24 months, when PHAC reports symptoms are most severe
  • Being born preterm, or having a condition that makes fluid loss harder to cope with

Others can often be worked on, usually with support from a health care team:

  • Hand washing after nappy changes and before preparing food, and cleaning surfaces, toys and shared equipment
  • Close contact with someone who has diarrhoea and vomiting, including on hospital wards, where a quarter of admissions in one Canadian study were acquired in hospital
  • Immunisation status, which depends on your province or territory’s schedule and the age windows NACI describes

How rotavirus is diagnosed in Canada

Most children are never tested. PHAC notes that routine laboratory testing is not standard practice, and that when a test is done the usual method is detection of rotavirus antigen in a stool sample by enzyme-linked immunoassay. In practice a clinician is more interested in how much fluid your child has lost, checking weight, alertness and urine output.

Treatment and day-to-day management

There is no medicine for the virus itself. Care is about fluid. Depending on how your child is doing, a health care team may discuss:

  • Oral rehydration solution, given in small, frequent amounts
  • Repeat hydration checks by a nurse or doctor
  • Intravenous fluids in hospital when a child cannot drink or is severely dehydrated
  • Continuing usual feeds and breastfeeding if a child can manage them
  • Two live oral vaccines authorised in Canada, RotaTeq and Rotarix. NACI describes starting at 6 weeks, with the first dose before 15 weeks and the series finished before 8 months. Severe combined immunodeficiency, previous intussusception and anaphylaxis to a component are listed as contraindications. What is funded is set by each province and territory

What suits one child will not suit another. These are decisions for you and your own clinician.

When to talk to a doctor

  • Call 911 or go to an emergency department if a child is very drowsy or floppy, cannot be woken, is not passing urine, or has sunken eyes and no tears.
  • Seek care the same day for a baby under 6 months with vomiting and diarrhoea, or any child who cannot keep fluid down.
  • Contact your health care provider for diarrhoea lasting more than a few days, blood in the stool, high fever or severe stomach pain.

Why clinical research matters for rotavirus

Canadian surveillance shows how much a publicly funded programme changes what a paediatric ward sees, and what is still unresolved. PHAC’s Canada Communicable Disease Report found laboratory-confirmed cases reported to the National Enteric Surveillance Program fell 54% between 2010 and 2017. But eligibility still differs by where a family lives, and the age windows are narrow, so babies who are unwell or premature at 6 weeks can miss the start. Open questions include how circulating strains shift, why the same vaccines behave differently in low-income countries where most rotavirus deaths happen, and how to reduce rotavirus acquired in hospital.

Taking part is voluntary. You give informed consent first, and you can stop at any time without affecting the care you get from your own clinicians. No one can say in advance whether a study will help you or your child.

Learn more from Canadian sources

Where this information comes from (5 sources)
  1. CMAJ Open, publicly funded rotavirus vaccine programmes and rotavirus in Canadian paediatric hospitals (IMPACT network), 2023
  2. Canadian Immunization Guide, rotavirus vaccine chapter, 2025
  3. Public Health Agency of Canada, Canada Communicable Disease Report 47(2), provincial rotavirus immunization programs, 2021
  4. Public Health Agency of Canada, rotavirus symptoms, 2018
  5. Johns Hopkins Bloomberg School of Public Health, rotavirus and childhood diarrhoeal deaths, The Lancet Global Health, 2024

This page is written in plain language for people considering clinical research. It is general health information, not medical advice, and it does not replace a conversation with your own doctor or nurse practitioner.

Common questions

How do I know whether my child is dehydrated?

The Public Health Agency of Canada lists dizziness, little or no urination, crying without tears, dryness in the throat and mouth, and unusual sleepiness or unresponsiveness as signs of dehydration. In a baby, fewer wet nappies than usual and being difficult to rouse are the ones to watch. Small, frequent amounts of oral rehydration solution are the mainstay of care. If a child cannot keep any fluid down, or is very drowsy, they need to be seen the same day.

What does NACI recommend about rotavirus immunisation?

The Canadian Immunization Guide describes two authorised oral vaccines, RotaTeq and Rotarix, given as a series starting at 6 weeks of age. The first dose is described as needing to be given before 15 weeks of age, with the series completed before 8 months, and doses can be given at the same visits as other routine infant vaccines. A three-dose schedule applies to one product and a two-dose schedule to the other. Severe combined immunodeficiency, a previous episode of intussusception and anaphylaxis to a vaccine component are listed as contraindications. Which product is used and who is eligible is decided by each province and territory.

Is rotavirus the same as food poisoning or the stomach flu?

No. Rotavirus is a specific virus spread through stool, usually hand to mouth or from contaminated surfaces and objects, not through contaminated food in the way salmonella or E. coli often are. It also has nothing to do with influenza, despite the phrase stomach flu. The Public Health Agency of Canada notes that symptoms begin 1 to 3 days after exposure and that diarrhoea usually lasts 3 to 8 days.

What to do next
  1. Talk to your doctor. This guide is information, not medical advice.
  2. Check for a match. Find your study match
  3. Not ready yet? Join the community and we will write to you when something opens.
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