A skin infection means an organism has taken hold in the skin. Three kinds cause them: bacteria, fungi and viruses. Treatment aimed at one does nothing for another.
Bacterial infections include cellulitis, which spreads through the deeper layers, impetigo, which crusts on the surface, and abscesses. Fungal infections include ringworm, athlete’s foot and nail infections. Viral ones include shingles, cold sores and warts.
Not every red, itchy or scaly patch is infected. Eczema, psoriasis and insect bites can look similar, and the Canadian Association of Emergency Physicians notes several non-infectious conditions are mistaken for cellulitis.
Fever or chills with any of these suggests the infection is not staying local.

Some risk factors cannot be changed:
Others can often be worked on, usually with support from a health care team:
Most are diagnosed by looking at the skin and asking how fast it is changing. For cellulitis the Canadian Association of Emergency Physicians states that diagnosis rests on clinical judgement rather than decision tools or biomarkers, and clinicians often mark the edge to see whether it advances. Fungal infection is where the laboratory matters: the Canadian Dermatology Association states the only accurate way to confirm a fungal nail infection is a clipping or scraping sent for microscopy and culture.
Treatment follows the organism. A clinician may discuss:
NACI also publishes shingles vaccine advice. These are decisions for you and your own clinician.
Antibiotic resistance is the central problem: Canadian Family Physician already advises against clindamycin here because of resistance and the risk of Clostridioides difficile. Canadian emergency physicians built a national checklist because of high rates of intravenous antibiotic use, hospitalisation and treatment failure. Studies are testing shorter antibiotic courses, oral rather than intravenous routes, outpatient pathways, faster identification of the organism, and new antifungals and antivirals.
Taking part is voluntary, informed consent comes first, you can stop at any time without affecting your regular care, and no one can say in advance whether a study will help you.
This page is written in plain language for people considering clinical research. It is general health information, not medical advice, and it does not replace a conversation with your own doctor or nurse practitioner.
Often you cannot tell at home, and that is a genuine difficulty rather than a failure to look properly. Eczema, psoriasis, insect bites, contact reactions and problems with the veins in the legs can all look like a skin infection, and the Canadian Association of Emergency Physicians notes that several conditions are commonly mistaken for cellulitis. The features that point towards infection are spreading over hours to days, warmth, increasing tenderness, and feeling unwell or feverish with it. A clinician looking at the skin, sometimes marking the edge to see whether it advances, is what settles it.
Because if the cause is a fungus, an antibacterial treatment has nothing to act on. Bacteria, fungi and viruses are different organisms and need different medicines. This is why identifying the group matters, and why the Canadian Dermatology Association states that the only accurate way to confirm a fungal nail infection is for a doctor to take a clipping or scraping and send it for microscopy and culture. Steroid creams can also make a fungal infection look better briefly while it spreads underneath.
Because antibiotic resistance is narrowing the options, and because Canadian emergency physicians documented high rates of intravenous antibiotic use, hospitalisation and treatment failure for these infections. Studies are testing shorter antibiotic courses, oral rather than intravenous treatment, outpatient pathways, faster ways to identify the organism, and new antifungal and antiviral agents. Taking part is voluntary, you give informed consent before anything begins, you can withdraw at any time without affecting your regular care, and no one can say in advance whether a study will help you personally.