RecruitingOsteoarthritis · Overweight and Obesity
Study for People With Excess Body Weight and Knee Osteoarthritis
Montreal, Quebec
Acute pain is pain that starts suddenly and has a clear cause: an injury, an operation, a medical procedure or a short-term illness. It is the body’s warning signal that something is wrong, and it usually eases as tissues heal, over days to a few weeks. That makes it different from chronic pain, which is pain lasting longer than three months.
Acute pain is not a milder version of chronic pain. It has an identifiable cause, a rough expected timeline, and it generally settles as healing happens, which is why it is assessed and managed differently. Long-lasting pain works through different mechanisms and is covered on our page for arthritis and chronic pain.
It is also not only a problem while it lasts. Some pain that starts as acute does not resolve on schedule: about 7.6 million people in Canada, roughly 1 in 5, live with chronic pain, and the Canadian Pain Task Force projected 9.0 million by 2030. Clinicians cannot yet tell in advance which people will move from short-term to long-lasting pain after an operation or an injury, and that unanswered question is one of the reasons acute pain is studied so closely.
How much pain a given injury or operation causes differs a great deal between people, and two people having the same procedure can need quite different plans.

Some risk factors cannot be changed:
Others can often be worked on, usually with support from a health care team:
Acute pain is assessed clinically rather than by a single test. In Canadian emergency departments, hospitals and clinics, staff ask you to rate the pain, often on a 0 to 10 scale, and ask where it is, what it feels like, what makes it better or worse, and how it affects your breathing, movement and sleep. An examination and, when needed, X-rays, scans or blood tests are used to find the cause and to rule out conditions that need urgent treatment. Many Canadian hospitals have acute pain services that follow patients after major surgery.
Clinical research for Acute Pain is enrolling. See the current studies
Canadian practice generally combines several approaches at once rather than relying on one medicine. Depending on the cause, the setting and your health history, a care team may discuss:
The mix that suits one person will not suit another, and it depends on the operation or injury, your other conditions and how you respond. These are decisions for you and your own care team rather than something this page can settle.
Two questions are still open. The first is how to control severe short-term pain well while limiting reliance on opioid medicines. The second is why some people go on to develop long-lasting pain after an operation or injury while others do not, since researchers cannot yet identify who is at highest risk of that shift. Trials under way are testing non-opioid pain medicines and new drug targets, regional anaesthesia and multimodal protocols, prehabilitation before planned surgery, and digital tools that track pain and recovery at home after discharge.
Studies in acute pain often recruit shortly before or right after a procedure, so the timing can be tight. Taking part is voluntary, you give informed consent before anything begins, and you can stop at any time without affecting the care you get from your own team. Joining a study does not mean giving up your usual pain management, and no one can say in advance whether a study will help you personally.
This page is written in plain language for people considering clinical research. It is general health information, not medical advice, and it does not replace a conversation with your own doctor or nurse practitioner.
Acute pain usually settles as tissues heal, which often takes days to a few weeks depending on the cause. Pain that is still there after about three months is generally described as chronic pain and is approached differently. If your pain is not easing on the timeline your clinician described, or is getting worse, contact your health care provider.
That is a decision made with your surgical or anaesthesia team, and it depends on the operation, your health history and how you respond to other options. Canadian practice generally combines several approaches, such as non-opioid medicines, nerve blocks and early movement, so that any opioid use can be kept as short as possible. Your team can explain the plan, how to store medicines safely and how to return leftovers to a pharmacy.
Common examples include studies of pain control after planned operations such as joint replacement or dental surgery, studies in emergency departments after fractures and other injuries, and studies of non-opioid medicines, nerve blocks or recovery programs. These trials often recruit shortly before or right after a procedure. A research team will explain what is involved and take your informed consent before anything begins.
RecruitingOsteoarthritis · Overweight and Obesity
Montreal, Quebec
RecruitingOsteoarthritis · Overweight and Obesity
Toronto & Stouffville, Ontario
Recruiting
RecruitingOsteoarthritis · Overweight and Obesity
Ontario · British Columbia
RecruitingHeadaches & Migraines · Pain
Sarnia, Ontario
RecruitingHeadaches & Migraines · Pain
Sarnia, Ontario