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Children’s Health (Pediatrics)

Plain-language information about children's health in Canada, written for parents, and the research enrolling now.
Plain-language guide, not medical advice
Reading time4 min
In CanadaUp to 80% of medicines off label
Studies recruitingNone right now

Children’s health covers babies, children and teenagers, from routine growth and immunisation through to conditions that look different in childhood than in adult life. Children are not small adults: their bodies handle medicines differently, and a young child cannot always tell you what is wrong. This page is written for a parent or guardian.

By the numbers in Canada
Up to 80%of medicines given in Canadian paediatric hospitals are prescribed off label, meaning they are used in an age group, dose form or way that was never formally studied in children.
Source: Canadian Paediatric Society, Improving paediatric medications, 2019, reaffirmed 2026

Conditions in this area

  • Otitis, or ear infection: about 75 per cent of children have at least one before school, showing up as ear pain, pulling at an ear, or a child who is unsettled and feverish.
  • Asthma: the airways narrow and become inflamed, causing cough, wheeze and breathlessness that is often worse at night or with running.
  • Rotavirus: a gut infection bringing watery diarrhoea and vomiting in babies and toddlers, where the real risk is dehydration.
  • Meningococcal disease and vaccination: uncommon but fast-moving, and the reason a fever with a stiff neck is an emergency.
  • HPV and HPV vaccination: a very common virus linked to several cancers later in life, which is why the vaccine is offered in school programs.
  • Eczema and atopic dermatitis: dry, itchy, inflamed skin affecting about 15 per cent of children in Canada, often disturbing the household’s sleep.
  • ADHD: a neurodevelopmental condition affecting attention, impulsivity and activity, diagnosed in about 8.4 per cent of children and youth aged 1 to 17 in 2023.
An adult and a child preparing a meal together at a kitchen table.
Most childhood conditions are assessed by a family doctor, nurse practitioner or paediatrician using growth charts, milestones and examination. Illustrative photograph.

What these conditions have in common

Several of these travel together. Eczema, asthma and allergy often appear in the same child and the same family, and treating one can make the others easier. Ear infections, rotavirus and meningococcal disease hit hardest in the first years of life, when the immune system is still learning and a small body loses fluid quickly. Poor sleep from eczema or untreated asthma can also look like the inattention of ADHD.

What links the whole list is a practical problem. Because medicines are developed and licensed in adults first, much of what is given to children has never been studied in children. The Canadian Paediatric Society reports that up to 80 per cent of medicines used in Canadian paediatric hospitals are prescribed off label. Clinicians work from the best evidence available, and paediatric research exists to replace that with proper evidence.

Treatment and management in Canada

Most children are looked after by a family doctor, nurse practitioner or paediatrician, using growth charts, milestones and examination rather than extensive testing. A team may discuss:

  • Pain relief and watchful waiting for many ear infections, with antibiotics when a clinician judges them needed
  • Inhaled medicines for asthma, with a written action plan and inhaler technique teaching
  • Moisturisers and topical anti-inflammatory treatment for eczema, with allergy assessment
  • Oral rehydration for gastroenteritis, and hospital care if a child is dehydrated
  • Routine immunisation, following your province or territory’s schedule
  • Behavioural support, school accommodations and, in some cases, medicines for ADHD

Children’s needs change as they grow, so what worked at two may not fit at eight. These are decisions for you and your child’s own clinician.

When to talk to a doctor

  • Trouble breathing, grunting, blue or grey lips, a rash like small bruises that does not fade when pressed, a stiff neck, a seizure, or a child who is very hard to wake needs emergency care. Call 911.
  • Any fever in a baby under three months old needs same-day assessment.
  • Dehydration, including far fewer wet nappies, no tears, a dry mouth or unusual drowsiness, needs same-day assessment.
  • Ear pain with high fever, or fluid from the ear, needs same-day assessment.
  • Concerns about growth, hearing, speech, learning or behaviour are worth an appointment, since support works better started early.
  • Trust your judgement. If your child seems different in a way you cannot explain, seek advice.

Why research in this area matters

Paediatric research often has to establish in children what is already known in adults: the right form of a medicine, the right amount for a child’s size, and how children respond over years rather than weeks. Trials in Canada also test vaccines in children, compare asthma and eczema treatments, and look at school-based programs for ADHD.

Research involving children in Canada follows the Tri-Council Policy Statement on research ethics. A parent or legal guardian gives consent, and where a child has some ability to understand what the research involves, the researcher must find out the child’s own wishes: a child’s refusal means they do not take part. Every study is reviewed by a research ethics board, participation is voluntary, and you can withdraw your child at any time without affecting their regular care. No one can say in advance whether a study will help a child.

Learn more from Canadian sources

Where this information comes from (5 sources)
  1. Canadian Paediatric Society, Improving paediatric medications: a prescription for Canadian children and youth (posted 2019, reaffirmed January 2026), 2026
  2. Statistics Canada, Canada's population estimates: age and gender, 1 July 2025, 2025
  3. Canadian Paediatric Society, management of acute otitis media in children six months of age and older, 2024
  4. Public Health Agency of Canada, chronic conditions in childhood, Canadian Health Survey on Children and Youth, 2023
  5. Tri-Council Policy Statement: Ethical Conduct for Research Involving Humans (TCPS 2), Chapter 3, Articles 3.9 and 3.10, 2022

This page is written in plain language for people considering clinical research. It is general health information, not medical advice, and it does not replace a conversation with your own doctor or nurse practitioner.

Common questions

Who gives consent for a child to join a study in Canada?

A parent or legal guardian gives consent. Canada's Tri-Council Policy Statement on research ethics also says that where a child has some ability to understand what the research involves, the researcher must find out the child's own wishes, and a child's refusal means they do not take part. Consent can be withdrawn at any time without affecting the child's regular care.

Why are children given medicines that were not tested in children?

Because most medicines are developed and licensed in adults first. The Canadian Paediatric Society reports that up to 80% of medicines used in Canadian paediatric hospitals are prescribed off label. Clinicians use the best evidence available, often from other countries or from experience, and paediatric research exists to replace that with proper evidence.

What protections apply when a child takes part in research?

No one can promise a particular outcome for any individual, in research or in routine care. What Canadian rules require is that a study is reviewed by a research ethics board, that risks are explained to you in plain language before you agree, that the study is designed for children rather than adapted from adults, and that you can stop at any time.

What to do next
  1. Talk to your doctor. This guide is information, not medical advice.
  2. Check for a match. Find your study match
  3. Not ready yet? Join the community and we will write to you when something opens.
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