25 studies recruiting now13 research sites across CanadaJoin the community
Medical condition

Asthma

Plain-language information about asthma in Canada, and the research enrolling for it now.
Plain-language guide, not medical advice
Reading time4 min
In CanadaMore than 4.6 million people
Studies recruiting6 now enrolling

Asthma is a long-term condition of the airways, the tubes that carry air in and out of your lungs. In asthma those tubes can swell, tighten and fill with mucus, so moving air takes more effort. Symptoms come and go, and they often flare after contact with a trigger such as a cold virus, cold air, exercise, smoke or an allergen.

By the numbers in Canada
4.6 millionpeople in Canada are living with asthma. Asthma Canada reports the total as more than that figure.
Source: Asthma Canada, National Asthma Survey, 2024
Worldwide363 million people worldwide were affected by asthma, and asthma was linked to 442,000 deaths.Source: World Health Organization, 2023

What asthma is, and what it is not

Asthma is often described as a childhood condition that people grow out of. It does often start in childhood, but it can begin at any age, including after 50. Adult-onset asthma is sometimes linked to workplace exposures, a chest infection, or allergies that develop later in life, and it is identified with the same breathing tests used in younger people.

Asthma is also not the same as COPD, although both narrow the airways and cause breathlessness. Asthma tends to vary from day to day and often improves a good deal after an inhaled bronchodilator, while the airflow limitation in COPD does not fully reverse. Some people have features of both. Because asthma varies, one normal breathing test does not always settle the question, which is why a clinician may repeat testing or add a challenge test.

Signs and symptoms

  • Wheezing, a whistling sound when you breathe out
  • Coughing, often worse at night or early in the morning
  • Shortness of breath, or feeling that you cannot get a full breath
  • Tightness or pressure in the chest
  • Waking at night because of coughing or breathing trouble
  • Getting more out of breath than usual during everyday activity
  • Needing a reliever inhaler more often than usual

Symptoms differ from person to person and change over time. Many people have long stretches with very little trouble, then a flare set off by a virus, cold air, exercise, smoke or an allergen.

A woman standing by an open balcony door with houseplants, looking outside on a bright day.
Indoor allergens, tobacco smoke, air pollution and wildfire smoke are among the asthma triggers a care team may review with you. Illustrative photograph.

What raises the risk

Some things cannot be changed:

  • A family history of asthma, eczema or hay fever
  • Being born early or with a low birth weight
  • Sex and age, with asthma more common in boys during childhood and in women during adulthood

Others can often be worked on, usually with support from a health care team:

  • Tobacco smoke, including second-hand smoke and vaping aerosol
  • Indoor allergens such as dust mites, mould, cockroaches and animal dander
  • Outdoor air pollution, traffic exhaust and wildfire smoke
  • Workplace exposures such as flour dust, isocyanates, wood dust and cleaning chemicals
  • Carrying extra weight, which is linked with harder-to-control asthma

How asthma is diagnosed in Canada

Asthma is usually confirmed with spirometry, a breathing test that measures how much air you can blow out and how fast, before and after an inhaled bronchodilator medicine. If spirometry is normal but asthma is still suspected, a methacholine challenge test or an exercise challenge test may be used to see whether the airways narrow. A clinician may also look at peak flow readings kept over time, arrange allergy testing by skin prick or blood IgE, and in some centres use a FeNO breath test that measures airway inflammation.

Treatment and day-to-day management

Clinical research for Asthma is enrolling. See the current studies

Asthma care in Canada aims to settle inflammation in the airways, keep symptoms from limiting your day, and lower the chance of a flare-up. Depending on how often you have symptoms and what sets them off, a health care team may discuss:

  • Inhaled medicines taken by puffer, spacer or nebuliser, including short-acting relievers and longer-acting controller inhalers that contain corticosteroids
  • Oral medicines, including corticosteroid tablets during a flare-up and leukotriene receptor antagonists
  • Biologic injectable therapies, handled through specialist severe asthma clinics for a small group of people whose symptoms continue on inhaled treatment
  • Asthma education and a written asthma action plan, from certified respiratory educators, pharmacists and family practices
  • Trigger assessment, allergy testing and allergen immunotherapy through allergists and respirologists

Inhaler technique, timing and choice all matter, and what suits one person will not suit another. These are decisions for you and your own clinician, and this page is not a recommendation about any of them.

When to talk to a doctor

  • Call 911 if you are struggling to breathe, cannot speak in full sentences, your lips or fingernails look blue or grey, or your reliever inhaler is not helping.
  • Seek urgent medical care the same day if you need your reliever inhaler more often than every four hours, or if symptoms keep waking you at night.
  • Book a review with your family doctor, nurse practitioner or pharmacist if you use a reliever inhaler more than twice a week, or if asthma is limiting your usual activities.

Why clinical research matters for asthma

A large share of people living with asthma in Canada still have symptoms despite treatment. Asthma Canada reported that only 45 percent of respondents to its 2024 national survey believed their asthma was well controlled. Researchers still do not fully understand why some people respond to standard inhalers while others do not, or how to pick out the different biological subtypes of asthma early. Studies running in Canada include new and existing biologic therapies for severe or eosinophilic asthma, single-inhaler anti-inflammatory reliever strategies, digital and connected inhaler tools that track how medicines are actually used, and research on air quality and wildfire smoke exposure.

Clinical studies are how those questions get answered. Taking part is voluntary, you give informed consent before anything begins, and you can stop at any time without affecting the care you get from your own doctor. Joining a study does not mean giving up your current treatment, and no one can say in advance whether a study will help you personally.

Learn more from Canadian sources

Where this information comes from (4 sources)
  1. Asthma Canada, A Snapshot of Asthma in Canada (National Asthma Survey), 2024
  2. Public Health Agency of Canada, Asthma and Chronic Obstructive Pulmonary Disease (COPD) in Canada, 2018
  3. Public Health Agency of Canada, Prevalence of chronic conditions in childhood, 2023
  4. World Health Organization, Asthma fact sheet, 2026

This page is written in plain language for people considering clinical research. It is general health information, not medical advice, and it does not replace a conversation with your own doctor or nurse practitioner.

Common questions

Can asthma start later in life?

Yes. Although asthma is often diagnosed in childhood, it can also begin in adulthood, including after age 50. Adult-onset asthma is sometimes linked to workplace exposures, respiratory infections or allergies that develop later, and it is diagnosed with the same breathing tests used in younger people.

How is asthma different from COPD?

Both conditions narrow the airways and cause breathlessness, but asthma tends to vary from day to day and often improves a good deal after an inhaled bronchodilator. COPD is usually linked to long-term exposure such as smoking and involves airflow limitation that does not fully reverse. Some people have features of both, and spirometry helps a clinician tell them apart.

Why might someone with asthma be invited to a clinical trial?

Trials look at questions current care has not answered, such as how to help people whose symptoms continue despite inhaled treatment. Taking part usually involves extra breathing tests and monitoring visits, and it is voluntary at every stage. A research team explains the study in detail during informed consent, and you can withdraw at any time.

What to do next
  1. Talk to your doctor. This guide is information, not medical advice.
  2. See the current studies. 6 studies for Asthma
  3. Not ready yet? Join the community and we will write to you when something opens.
Research studies

Studies for Asthma

See all Asthma trials →

Learn more about Asthma

Health blog →

Connecting Canadians with clinical research studies conducted by a network of physicians committed to advancing medicine — since 1995.

JoinAStudy.ca provides information about clinical research and does not provide medical advice, diagnosis, or treatment. Only a qualified study doctor can determine your eligibility for a study. Participation is always voluntary.

© 2026 JoinAStudy.ca · A network of Canadian physicians.|Designed by Pixelore.ca