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Home/Current studies/Weight Management Study in Individuals With Obesity and…
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Weight Management Study in Individuals With Obesity and Type 2 Diabetes

Enrolling at: London
Phase 3Study phase
18+Age range
1 siteResearch locations

About this study

Are you struggling with being overweight, and also have type 2 diabetes?

The purpose of this study is to find out whether an experimental medication helps people living with obesity and type 2 diabetes to lose weight.

Would you like to take part?

As a volunteer in a research study, you’ll receive study-related medical care from the study doctor and regular follow-up of your health to monitor the effectiveness of the care you’ll receive. The results of this research will be used to find out if the investigational medication being studied will be of benefit to others struggling with obesity and weight loss, and whether it will be made widely available to all Canadians trying to manage obesity. Study volunteers are an important part of moving medical care forward.

Who may qualify

You may qualify if
  • Are female or male, 18 years of age or older at the time of signing informed consent
  • Have a history of at least one self-reported unsuccessful dietary effort to lose body weight
  • Have a body mass index (BMI) greater than or equal to 27 kg/m^2
  • Have been diagnosed with type 2 diabetes > 180 days before screening
  • Are currently being treated with either lifestyle intervention or:
    • Stable treatment for at least 90 days before screening with 1-3 marketed oral antidiabetic drugs as a single agent or in combination, according to local practice
    • For up to 30% of participants the following concomitant medication is allowed:
      • Treatment for any indication with a stable dose of glucagon-like peptide-1 (GLP-1) containing medication, stable for at least 1 year before screening
      • Treatment with basal insulin minimum stable for at least 90 days before screening
This study may not be a fit if
  • Have been treated with any type of insulin within 90 days before screening apart from those randomized under the above criteria
  • Have been treated or intent to treat with any medication prescribed for the indication of weight management within 180 days before screening
  • Have had any clinically significant or severe hypoglycemic episodes with 180 days before screening
  • Have uncontrolled and potentially unstable diabetic retinopathy or maculopathy
  • Have uncontrolled thyroid disease
Every study has additional criteria the research site will review with you.

What participation may involve

  • Regular visits with the study team at no cost
  • Study assessments and health monitoring throughout
  • Check-ins between visits
  • Informed consent before anything begins — questions welcome

What participants may receive

  • Study-related care from a physician-led team
  • Study assessments at no cost
  • Reimbursement for reasonable travel, where applicable
Specifics vary by study and site, and are never a guarantee of benefit. Being in a study is not a substitute for regular medical care.
Participating research sites

Where this study is enrolling

LONDON, ONLondon East Medical CentrePrincipal investigator: Dr. Peter DzongowskiView site →

Learn more

About the condition

Diabetes

Diabetes means the level of sugar, or glucose, in your blood stays too high because your body cannot make enough insulin or cannot use the insulin it makes.…

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About the condition

General Health

General health is the part of clinical research that is not built around a single diagnosis: prevention, vaccines, healthy ageing, weight and smoking, and studies that need volunteers…

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About the condition

Weight Conditions (Overweight, Obesity)

Obesity is a long-term medical condition in which extra body fat builds up to a point where it can affect health. Canadian clinical guidelines describe it as a…

Learn about this condition →
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Common questions

Do I have to decide now?
No. Answering the questions is not a commitment — it simply lets the research team see whether this study may be appropriate and contact you to talk it through.
Will it cost me anything?
No. Study visits and study assessments are provided at no cost, and reasonable travel may be reimbursed where applicable.
What happens after I submit the form?
A member of the research team reviews your answers and contacts you — usually within two business days — to answer questions and review the next steps.
Could I receive a placebo?
Some studies compare a treatment with a placebo. Whether this study does is explained clearly during informed consent, before you decide anything.
Can I leave the study after it starts?
Yes. Participation is always voluntary. You can withdraw at any time without giving a reason and without it affecting your regular medical care.
Request contact

Ask the research site to contact you

Your answers go only to the research site, help the team prepare before they call — and completing the form doesn’t obligate you to take part.
JAS Study Interest (Stream A)

See if you may qualify

A few quick questions — about a minute. Your answers help the research team prepare before they contact you.

For anyone under 18, a parent or legal guardian should complete this form and would need to consent on their behalf.

See if you may qualify →

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