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Migraines and Headaches

Plain-language information about migraine and headache disorders in Canada, and the research enrolling for them now.
Plain-language guide, not medical advice
Reading time5 min
In Canada5 million+ affected by migraine
Studies recruiting5 now enrolling

Migraine is a neurological condition, not just a bad headache. An attack usually brings moderate to severe head pain along with nausea and sensitivity to light, sound or smell, and it can last from a few hours to a few days. Tension-type headache, cluster headache and medication-overuse headache are separate conditions with their own patterns, and telling them apart is what shapes the care you are offered.

By the numbers in Canada
5 million+Canadians are affected by migraine, according to Migraine Canada, the national patient organisation for the condition.
Source: Migraine Canada, 2025
  • Statistics Canada found that 8.3% of Canadians, about 2.7 million people, reported being diagnosed with migraine by a health professional. The figure was 11.8% among females and 4.7% among males, so women were more than twice as likely to report migraine. Source: Statistics Canada, Health Reports, 2014
  • Migraine most often begins and peaks during working and caregiving years. Prevalence was highest at ages 30 to 49 for both sexes, fewer than 1% of children under 12 reported migraine, and the average age at diagnosis was 26.2 years, about 3.6 years after symptoms started. Source: Statistics Canada, Health Reports, 2014
  • Migraine reaches well into daily life. Among Canadians with migraine, 76% reported that it limited their sleep quality, 53% said it had prevented them from driving, 30% reported limits on educational opportunities, and 36% of those employed had missed at least one workday in the previous three months. Source: Statistics Canada, Health Reports, 2014
Worldwide3.1 billion people, about 40% of the global population, were affected by headache disorders in 2021. Migraine ranked as the third highest cause of disability-adjusted life years worldwide that year, after stroke and neonatal encephalopathy.Source: World Health Organization, 2024

Migraine and tension-type headache are not the same thing

In migraine, the brain’s pain and sensory processing is temporarily disrupted. That is why an attack so often arrives with nausea and a need for a dark, quiet room, why some people notice warning signs such as yawning, food cravings, neck stiffness or mood changes in the hours beforehand, and why a day of feeling drained and foggy can follow. The World Health Organization ranks migraine as the third highest cause of disability-adjusted life years worldwide.

Tension-type headache feels different: a steady, band-like pressure on both sides of the head, without the nausea and without pain that worsens sharply when you move. Cluster headache is different again. Medication-overuse headache can develop when acute headache treatments are taken on many days each month over a long period, and the World Health Organization describes it as the most common secondary headache disorder, affecting up to 5% of some populations. This is why clinicians pay more attention to the pattern of your headaches over weeks than to how bad any single one was.

Signs and symptoms

  • Throbbing or pounding head pain, often on one side, that gets worse with movement
  • Nausea, vomiting or loss of appetite during an attack
  • Sensitivity to light, sound or smells, so you want a dark quiet room
  • Aura before or during an attack in some people, such as flashing lights, zigzag lines, blind spots, or tingling in the face or hand
  • Warning signs in the hours or day before, such as yawning, food cravings, neck stiffness or mood changes
  • Feeling drained, foggy or washed out for a day afterwards
  • Tension-type headache feels different: steady band-like pressure on both sides, without nausea

Attack frequency varies widely, from a few times a year to most days of the month, and the pattern can change over a lifetime, particularly around hormonal changes.

A woman sitting at an outdoor cafe table wearing sunglasses, one hand raised to her temple.
Sensitivity to light and sound is part of a migraine attack for many people rather than a separate problem. Illustrative photograph.

What raises the risk

Some risk factors cannot be changed:

  • Family history, since migraine often runs in families
  • Being female, which is linked to more than double the reported rate in Canada
  • Hormonal changes across the menstrual cycle, pregnancy and menopause
  • Age, with prevalence peaking between 30 and 49

Others can often be worked on, usually with support from a health care team:

  • Irregular sleep, skipped meals, dehydration and high stress, which are common attack triggers
  • Frequent use of acute headache medicines, which is linked to medication-overuse headache
  • Untreated depression, anxiety or sleep disorders, which travel with more frequent attacks

How migraine is diagnosed in Canada

Migraine is diagnosed clinically, usually by a family doctor or nurse practitioner, based on the pattern of your attacks rather than a scan or blood test. Your clinician will ask how often headaches happen, how long they last, what the pain is like, what comes with it, and what makes it better or worse. A headache diary, or a questionnaire such as the MIDAS or HIT-6, is often used to track frequency and impact over time. Imaging is generally reserved for people whose headaches have warning features or an unusual pattern, and some people are referred to a neurologist or a headache clinic.

Treatment and day-to-day management

Clinical research for Migraines and Headaches is enrolling. See the current studies

Care usually has two halves: something to take during an attack, and, for people with frequent attacks, something taken regularly to make attacks less frequent. Depending on your pattern and your other health conditions, a health care team may discuss:

  • Acute or as-needed treatments taken at the start of an attack, including simple analgesics, anti-inflammatory medicines, triptans and newer targeted acute medicines, with attention to how many days per month they are used
  • Preventive medicines taken regularly to lower attack frequency, including certain blood pressure medicines, antidepressants, anticonvulsants, and treatments that target the CGRP pathway
  • Procedures and devices, including botulinum toxin injections for chronic migraine, nerve blocks, and neuromodulation devices
  • Non-drug approaches, including cognitive behavioural therapy, relaxation and biofeedback, regular sleep and meal routines, physiotherapy for neck-related symptoms, and headache diaries to identify patterns
  • Care for conditions that travel with migraine, such as depression, anxiety and insomnia, and a review for medication-overuse headache where acute treatments are being used frequently

Which preventive suits a given person is not predictable in advance, and finding a workable plan often takes more than one attempt. These are decisions for you and your own clinician rather than something this page can settle.

When to talk to a doctor

  • Call 911 or go to an emergency department immediately for a thunderclap headache, meaning a sudden severe headache that reaches its worst intensity within about a minute. This can signal bleeding in or around the brain.
  • Call 911 for a headache with new weakness or numbness on one side, a drooping face, trouble speaking or understanding, vision loss, confusion or a seizure, or for a headache after a significant head injury.
  • Seek urgent care for a headache with fever and a stiff neck or a new rash, for a headache that steadily worsens over days or weeks, for a new headache pattern after age 50, or for a headache that is much worse when you cough, strain or lie down.

Why clinical research matters for migraine

Migraine is common and disabling, yet many people in Canada wait years for a diagnosis, and access to headache specialists and to newer preventive treatments varies by province and by drug plan. Researchers still cannot predict which preventive treatment will work for a given person, and a meaningful share of people do not respond well to the options available. Trials under way include newer CGRP-targeting and other mechanism-specific medicines for both acute treatment and prevention, neuromodulation devices, treatments for cluster headache and medication-overuse headache, digital cognitive behavioural therapy and behavioural programs, and studies in groups that have been under-represented in past research.

Clinical studies are how those questions get settled. Most ask you to keep a headache diary for a period before and during the trial. Taking part is voluntary, you give informed consent before anything begins, and you can stop at any time without affecting the care you get from your own doctor. No one can say in advance whether a study will help you personally.

Learn more from Canadian sources

Where this information comes from (4 sources)
  1. Migraine Canada, 2025
  2. Statistics Canada, Health Reports, Prevalence of migraine in the Canadian household population, 2014
  3. World Health Organization, Migraine and other headache disorders fact sheet, 2024
  4. Health Canada, Canadian Pain Task Force, An Action Plan for Pain in Canada, 2021

This page is written in plain language for people considering clinical research. It is general health information, not medical advice, and it does not replace a conversation with your own doctor or nurse practitioner.

Common questions

Is migraine just a very bad headache?

No. Migraine is a neurological condition in which the brain's pain and sensory processing is temporarily disrupted, which is why attacks often bring nausea and sensitivity to light and sound as well as head pain. Many people also have warning symptoms before an attack and feel drained for a day afterward. The World Health Organization ranks migraine as the third highest cause of disability-adjusted life years worldwide.

Can headache medicines make headaches more frequent?

Yes, this is recognised as medication-overuse headache, and the World Health Organization describes it as the most common secondary headache disorder, affecting up to 5% of some populations. It can develop when acute headache treatments are taken on many days each month over a long period. If you are reaching for acute treatment frequently, tell your health care provider, since the plan usually needs to be reviewed rather than simply continued.

Who takes part in migraine clinical trials?

Trials recruit across the spectrum, from people with a few attacks a month to people with chronic migraine of 15 or more headache days a month, and some focus on people who have not done well on previous preventives. Studies typically ask you to keep a headache diary for a period before and during the trial. Taking part is voluntary, requires informed consent, and you can stop at any time.

What to do next
  1. Talk to your doctor. This guide is information, not medical advice.
  2. See the current studies. 6 studies for Migraines and Headaches
  3. Not ready yet? Join the community and we will write to you when something opens.
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