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Home/Current studies/A Research Study of Insulin Icodec in Adults…
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A Research Study of Insulin Icodec in Adults With Type 2 Diabetes

Enrolling at: Montreal
Phase 4Study phase
18+Age range
1 siteResearch locations

About this study

Do you have type 2 diabetes and are currently struggling to control your glucose levels?

This clinical research study is evaluating an experimental treatment for type 2 diabetics.

This study compares insulin icodec, taken once a week, with other basal insulins, taken once a day, in people with type 2 diabetes. The purpose of this study is to see how well the approved injectable weekly insulin icodec maintains blood sugar levels when compared to approved and available daily injectable basal insulins in people with type 2 diabetes. The participants will either be prescribed weekly insulin icodec or a daily basal insulin (insulin glargine, insulin detemir or insulin degludec) based on current standards for the treatment of type 2 diabetes. The study will last for about 13 months.

As a volunteer in a research study, you’ll receive study-related medical care from the study doctor and regular follow-up of your health to monitor the effectiveness of the care you’ll receive. The results of this research will be used to find out if the investigational medication being studied will be of benefit to others struggling to manage type 2 diabetes, and whether it will be made widely available to all Canadians. Study volunteers are an important part of moving medical care forward.

Who may qualify

You may qualify if
  • Have been diagnosed with type 2 diabetes greater than or equal to (≥) 180 days prior to the day of screening
  • Have been treated with any of the following non-insulin glucose-lowering medication(s) or combination regimen(s) at the time of screening:
    • Metformin, Sulfonylureas, Meglitinides (glinides), dipeptidyl peptidase-4 (DPP-4) inhibitors, sodium-glucose cotransporter-2 (SGLT2) inhibitors, Thiazolidinediones, Alpha-glucosidase inhibitors, Oral combination products (for the allowed individual oral antidiabetic drugs), Oral or injectable glucagon-like peptide-1 (GLP-1) receptor agonists and Injectable dual glucose-dependent insulinotropic polypeptides (GIP) and GLP-1 receptor agonist.
  • Have need of intensification with basal insulin, as indicated at the discretion of the investigator.
  • Have recorded HbA1c value ≥7% within the last 90 days prior to randomization.
This study may not be a fit if
  • Have any known or suspected hypersensitivity to study intervention(s) or related products.
  • Have any previous participation in this study. Participation is defined as signed informed consent.
  • Are a female who is pregnant, breast-feeding or intends to become pregnant or is of child-bearing potential and not using an adequate contraceptive method.
  • Have previously participated (i.e., received any study intervention) in any interventional clinical study within 90 days before screening.
  • Have any disorder which, in the investigator’s opinion, might jeopardize your safety.
Every study has additional criteria the research site will review with you.

What participation may involve

  • Regular visits with the study team at no cost
  • Study assessments and health monitoring throughout
  • Check-ins between visits
  • Informed consent before anything begins — questions welcome

What participants may receive

  • Study-related care from a physician-led team
  • Study assessments at no cost
  • Reimbursement for reasonable travel, where applicable
Specifics vary by study and site, and are never a guarantee of benefit. Being in a study is not a substitute for regular medical care.
Participating research sites

Where this study is enrolling

MONTREAL, QCEndocrinologie OasisPrincipal investigator: Dr. Zeina YaredView site →

Learn more

About the condition

Diabetes

Diabetes means the level of sugar, or glucose, in your blood stays too high because your body cannot make enough insulin or cannot use the insulin it makes.…

Learn about this condition →
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Other studies you can explore

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RecruitingA Study of Eloralintide in Participants With Obesity, or Overweight Without Type 2 DiabetesSarnia · HamiltonCheck availability →Enrolment closedWeight Management Study in Individuals With Obesity and Type 2 DiabetesLondonView study →Enrolment closedStudy of Insulin Icodec in Adults with Type 1 DiabetesMontrealView study →

Common questions

Do I have to decide now?
No. Answering the questions is not a commitment — it simply lets the research team see whether this study may be appropriate and contact you to talk it through.
Will it cost me anything?
No. Study visits and study assessments are provided at no cost, and reasonable travel may be reimbursed where applicable.
What happens after I submit the form?
A member of the research team reviews your answers and contacts you — usually within two business days — to answer questions and review the next steps.
Could I receive a placebo?
Some studies compare a treatment with a placebo. Whether this study does is explained clearly during informed consent, before you decide anything.
Can I leave the study after it starts?
Yes. Participation is always voluntary. You can withdraw at any time without giving a reason and without it affecting your regular medical care.
Request contact

Ask the research site to contact you

Your answers go only to the research site, help the team prepare before they call — and completing the form doesn’t obligate you to take part.
JAS Study Interest (Stream A)

See if you may qualify

A few quick questions — about a minute. Your answers help the research team prepare before they contact you.

For anyone under 18, a parent or legal guardian should complete this form and would need to consent on their behalf.

See if you may qualify →

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