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Home/Current studies/A Study of Eloralintide in Participants With Obesity,…
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A Study of Eloralintide in Participants With Obesity, or Overweight Without Type 2 Diabetes

Enrolling at: Sarnia · Hamilton
Phase 3Study phase
18+Age range
2 sitesResearch locations

About this study

Are you Struggling With Obesity, or Being Overweight?

The purpose of this study is to find out whether an experimental medication helps people living with obesity to lose weight.

The purpose of this study is to evaluate the efficacy and safety of eloralintide in adults with obesity or overweight who do not have type 2 diabetes. The study has two phases: a main phase and an extension phase.

Participation in the main phase of the study will last about 75 weeks. Participants with prediabetes will continue in the extension phase for another 2 years.

Would you like to take part?

As a volunteer in a research study, you’ll receive study-related medical care from the study doctor and regular follow-up of your health to monitor the effectiveness of the care you’ll receive. The results of this research will be used to find out if the investigational medication being studied will be of benefit to others struggling with obesity and weight loss, and whether it will be made widely available to all Canadians trying to manage obesity. Study volunteers are an important part of moving medical care forward.

Who may qualify

You may qualify if
  • Have Body Mass Index (BMI) at screening of the following:
    • 30 kilogram per square meter (kg/m2) OR
    • 27 kg/m2 with at least one of the following weight-related health conditions at screening:
      • high blood pressure
      • dyslipidemia
      • obstructive sleep apnea, or
      • heart disease
  • Have had a stable body weight (<5% body weight change) for 90 days prior to screening.
  • Have a history of at least one self-reported unsuccessful dietary effort to reduce body weight.
This study may not be a fit if
  • Have had a prior or planned surgical treatment for obesity (liposuction, cryolipolysis, or abdominoplasty allowed if performed >1 year before screening)
  • Have had a prior or planned endoscopic procedure and/or device-based therapy for obesity (prior device-based therapy acceptable if device removal was more than 6 months prior to screening)
  • Have type 1 diabetes or type 2 diabetes
  • Have had within 90 days prior to screening:
    • heart attack
    • stroke
    • coronary artery revascularization
    • unstable angina, or
    • hospitalization due to congestive heart failure
  • Have a history or diagnosis of New York Heart Association Functional Classification Class IV congestive heart failure
  • Have taken medications or alternative remedies intended for weight loss within 90 days of screening.
Every study has additional criteria the research site will review with you.

What participation may involve

  • Regular visits with the study team at no cost
  • Study assessments and health monitoring throughout
  • Check-ins between visits
  • Informed consent before anything begins — questions welcome

What participants may receive

  • Study-related care from a physician-led team
  • Study assessments at no cost
  • Reimbursement for reasonable travel, where applicable
Specifics vary by study and site, and are never a guarantee of benefit. Being in a study is not a substitute for regular medical care.
Participating research sites

Where this study is enrolling

SARNIA, ONBluewater Clinical Research GroupPrincipal investigator: Dr. John O’Mahony, Dr. Sean PetersonView site →HAMILTON, ONWinterberry Family MedicinePrincipal investigator: Dr. Steven V. ZizzoView site →

Learn more

About the condition

Diabetes

Diabetes means the level of sugar, or glucose, in your blood stays too high because your body cannot make enough insulin or cannot use the insulin it makes.…

Learn about this condition →
About the condition

General Health

General health is the part of clinical research that is not built around a single diagnosis: prevention, vaccines, healthy ageing, weight and smoking, and studies that need volunteers…

Learn about this condition →
About the condition

Weight Conditions (Overweight, Obesity)

Obesity is a long-term medical condition in which extra body fat builds up to a point where it can affect health. Canadian clinical guidelines describe it as a…

Learn about this condition →
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Common questions

Do I have to decide now?
No. Answering the questions is not a commitment — it simply lets the research team see whether this study may be appropriate and contact you to talk it through.
Will it cost me anything?
No. Study visits and study assessments are provided at no cost, and reasonable travel may be reimbursed where applicable.
What happens after I submit the form?
A member of the research team reviews your answers and contacts you — usually within two business days — to answer questions and review the next steps.
Could I receive a placebo?
Some studies compare a treatment with a placebo. Whether this study does is explained clearly during informed consent, before you decide anything.
Can I leave the study after it starts?
Yes. Participation is always voluntary. You can withdraw at any time without giving a reason and without it affecting your regular medical care.
Request contact

Ask the research site to contact you

Your answers go only to the research site, help the team prepare before they call — and completing the form doesn’t obligate you to take part.
JAS Study Interest (Stream A)

See if you may qualify

A few quick questions — about a minute. Your answers help the research team prepare before they contact you.

For anyone under 18, a parent or legal guardian should complete this form and would need to consent on their behalf.

See if you may qualify →

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