Insulin Icodec Type 1 Diabetes Study

About this study

Do you have Type 1 Diabetes and also struggle with weight management?

This study will compare insulin icodec, an insulin taken once a week, to insulin glargine, an insulin taken once a day. The study medicine will be investigated in participants with type 1 diabetes. The study will look at how well insulin icodec taken weekly controls blood sugar compared to insulin glargine taken daily. The study will last for about 8.5 months.

Would you like to take part? Would you like a friend or family member to take part?

As a volunteer in a research study, you will receive personal study-related medical care from the study doctor and regular follow up on your type 1 diabetes to monitor the effectiveness of the care you will receive. The results of this research will be used to find out if the experimental medication being studied will be of benefit to others with type 1 diabetes or not. Study volunteers are an important part of moving medical care forward.

Who may qualify

You may qualify if

Have been diagnosed with type 1 diabetes mellitus greater than or equal to (≥) 1 year before screening.
Have been treated with multiple daily insulin injections (daily basal insulin analogue and bolus insulin analogue regimen) ≥ 6 months before screening.
Have HbA1c levels from 7.0-10.0 percentage (%) (53.0-85.8 millimoles per mole (mmol/mol)), both inclusive, at screening confirmed by central laboratory analysis.
Have an ability and willingness to adhere to the protocol including performance of self-measured plasma glucose (SMPG) profiles, based on the investigator’s judgement

This study may not be a fit if

Have any known or suspected hypersensitivity to study intervention(s) or related products.
Have previously participated in this study. Participation is defined as signed informed consent.
Are a female who is pregnant, breast-feeding or intends to become pregnant or is of childbearing potential and not using adequate contraceptive method.
Have been exposed to an investigational medicinal product within 90 days or 5 half-lives of the investigational medicinal product (if known), whichever is longer, before screening.
Have any condition, except for conditions associated with type 1 diabetes mellitus, which in the investigator’s opinion might jeopardise participant’s safety or compliance with the protocol.
Have any anticipated initiation or anticipated change in concomitant medications (for more than 15 consecutive days) known to affect weight or glucose metabolism (e.g., treatment with thyroid hormones, or systemic corticosteroids).
Have known hypoglycaemic unawareness as indicated by the Investigator according to Clarke’s questionnaire question.
Have had any recurrent severe hypoglycaemic episodes within the last year as judged by the investigator

Every study has additional criteria the research site will review with you.

Participants who qualify for this study will receive a study-related health examination at no cost, as well as possible compensation for time and travel.

What participation may involve

Regular visits with the study team at no cost
Study assessments and health monitoring throughout
Check-ins between visits
Informed consent before anything begins — questions welcome

What participants may receive

Study-related care from a physician-led team
Study assessments at no cost
Reimbursement for reasonable travel, where applicable

Specifics vary by study and site, and are never a guarantee of benefit. Being in a study is not a substitute for regular medical care.

Participating research sites

Where this study is enrolling

MONTREAL, QCEndocrinologie OasisPrincipal investigator: Dr. Zeina YaredView site →

Learn more

About the condition

Diabetes

Diabetes means the level of sugar, or glucose, in your blood stays too high because your body cannot make enough insulin or cannot use the insulin it makes.…

Learn about this condition →

Other studies you can explore

All current studies →

RecruitingA Study of Eloralintide in Participants With Obesity, or Overweight Without Type 2 DiabetesSarnia · HamiltonCheck availability →

Enrolment closedWeight Management Study in Individuals With Obesity and Type 2 DiabetesLondonView study →

RecruitingA Research Study of Insulin Icodec in Adults With Type 2 DiabetesMontrealCheck availability →

Common questions

Do I have to decide now?

No. Answering the questions is not a commitment — it simply lets the research team see whether this study may be appropriate and contact you to talk it through.

Will it cost me anything?

No. Study visits and study assessments are provided at no cost, and reasonable travel may be reimbursed where applicable.

What happens after I submit the form?

A member of the research team reviews your answers and contacts you — usually within two business days — to answer questions and review the next steps.

Could I receive a placebo?

Some studies compare a treatment with a placebo. Whether this study does is explained clearly during informed consent, before you decide anything.

Can I leave the study after it starts?

Yes. Participation is always voluntary. You can withdraw at any time without giving a reason and without it affecting your regular medical care.

Request contact

Ask the research site to contact you

Your answers go only to the research site, help the team prepare before they call — and completing the form doesn’t obligate you to take part.

JAS Study Interest (Stream A)

See if you may qualify

A few quick questions — about a minute. Your answers help the research team prepare before they contact you.

Who may take part in this study?

Myself

Someone I care for

Age of the person who may take part

For anyone under 18, a parent or legal guardian should complete this form and would need to consent on their behalf.

Has a doctor diagnosed you (or the person who may take part) with the condition this study is about?

Yes

Not sure

Postal code (first 3 characters are enough)

Study of Insulin Icodec in Adults with Type 1 Diabetes

About this study

Who may qualify

What participation may involve

What participants may receive

Where this study is enrolling

Learn more

Diabetes

Other studies you can explore

Common questions

Ask the research site to contact you

See if you may qualify

How can we reach you?

Find a study

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